Simple enough topic...criteria is completely open, with the caveat being you can only choose one game. No hedging and listing 3 or 4 different games. Here is my nomination...
Sid Luckman's performance in the 1943 NFL Championship game.
15 of 26 for 286 yards passing, 5 TD 0 INT, 8 carries for 64 yards rushing, 2 punt returns for 32 yards, 3 punts for 74 yards, 2 INTs for 39 yards.
Some interesting plays in the game footage. Looks like a bubble screen at the 0:15 mark, and a middle WR screen at the 1:19 mark. Staple plays for today's spread offenses (especially in college).